Neuroinflammation and Stroke Pathogenesis

Neuroinflammation plays a pivotal role in the pathogenesis of stroke, contributing to the cascade of events that exacerbate brain damage. Following an ischemic stroke, the release of pro-inflammatory cytokines and activation of immune cells trigger an inflammatory response within the brain. This neuroinflammatory process can lead to the breakdown of the blood-brain barrier, increased oxidative stress, and the recruitment of immune cells, further amplifying the inflammatory cascade. Ultimately, neuroinflammation exacerbates neuronal injury and impairs recovery. Understanding the intricate interplay between neuroinflammation and stroke pathogenesis is crucial for developing targeted therapies aimed at modulating the inflammatory response, promoting brain repair, and improving outcomes for stroke patients.

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